hrp0084p2-269 | Diabetes | ESPE2015

Clinical and Hormonal Profile in Mini-Puberty of Daughters Born after Pregnancies with Diabetes: Preliminary Report

Riquelme Joel , Martinez Daniela , Sir-Petermann Teresa , Villarroel Claudio , Codner Ethel

Background: Maternal diabetes is a pathologic state that increases the incidence of complications in both the mother and the foetus. Patients with diabetes mellitus (DM) may exhibit reproductive abnormalities, including PCOS and hypogonadotropic hypogonadism. Diabetes during pregnancy is an endocrine disruptor and studies performed in animal models have shown abnormalities in gonadal function in the offspring, but it is unknown whether pre-gestational (PGDM) and gestational di...